1-(4-Fluorophenyl)-4-[1,2,3,6-tetrahydro -4-(phenylthio)-1-pyrid

Details 1-(4-Fluorophenyl)-4-[1,2,3,6-tetrahydro -4-(phenylthio)-1-pyrid 1-(4-Fluorophenyl)-4-[1,2,3,6-tetrahydro -4-(phenylthio)-1-pyrid

1978-07-10

1980-08-19

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546294, 546301, A61K 3144, C07D21304

Patent

active

042184550

ABSTRACT:
Tetrahydropyridylbutyrophenones of the following formula IX: ##STR1## wherein x is hydrogen, halogen such as fluorine, chlorine, bromine or iodine, trifluoromethyl, alkoxy, nitro, cyano, amino, lower alkyl of 1 to 6 carbons, aryl or substituted aryl; y is hydrogen or halogen; and n is 0, 1 or 2; and the non-toxic, pharmaceutically acceptable acid addition salts thereof. Tetrahydropyridylbutanols having the formula X: ##STR2## wherein x and y are as defined above, as well as their non-toxic, pharmaceutically acceptable acid addition salts, are also disclosed. The compounds of the invention having the formulas IX and X are useful as antipsychotics.

REFERENCES:
patent: 4128552 (1978-12-01), Wise et al.
patent: 4134982 (1979-01-01), Wise et al.

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