Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1977-01-18
1978-07-11
Demers, Arthur P.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
542418, 544353, 544355, C07D23976
Patent
active
041002849
ABSTRACT:
The invention relates to novel chemical compounds which have useful antibacterial properties and are also of value in promoting animal growth and improving animal feed efficiency. More specifically, these new chemical compounds are certain sulfonylhydrazones of 1,4-dioxoquinoxaline-2-carboxaldehyde, 4-oxoquinoxaline-2-carboxaldehyde and certain derivatives thereof of formula (I): ##STR1## wherein A is N or N .fwdarw. O; R is a member selected from the group consisting of alkyl having from one to five carbon atoms, trifluoromethyl, phenyl, npahthyl, benzyl, styryl and phenyl substituted by up to two members selected from the group consisting of Cl, F, Br, CH.sub.3, CH.sub.3 O and NO.sub.2 ; R.sup.1 is hydrogen or methyl; R.sup.2 is hydrogen or methyl; R.sup.3 is a 6- or 7-position substituent and is selected from the group H, Cl, CH.sub.3, CH.sub.3 O, SO.sub.2 NH.sub.2, SO.sub.2 NHCH.sub.3 and SO.sub.2 N(CH.sub.3).sub.2 ; R.sup.4 is a 7- or 6-position substituent and is selected from the group H, Cl and CH.sub.3 ; with the proviso that when R.sup.4 is Cl or CH.sub.3, R.sup.3 and R.sup.4 are the same.
REFERENCES:
patent: 3371090 (1968-02-01), Johnston
patent: 3493572 (1970-02-01), Johnston
patent: 3819616 (1974-06-01), Seng et al.
patent: 3839326 (1974-10-01), Seng et al.
patent: 3928608 (1975-12-01), Cox et al.
patent: 3931174 (1976-01-01), McFarland
Sartorelli et al., J. Med. Chem., 19 (1976), pp. 830-833.
Demers Arthur P.
Pfizer Inc.
LandOfFree
1,4-Dioxo- and 4-oxoquinoxaline-2-carboxaldehyde sulfonylhydrazo does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1,4-Dioxo- and 4-oxoquinoxaline-2-carboxaldehyde sulfonylhydrazo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,4-Dioxo- and 4-oxoquinoxaline-2-carboxaldehyde sulfonylhydrazo will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-262717