Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-10-21
1990-06-19
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514344, 546321, 546286, C07D21186, A61K 31455
Patent
active
049355481
ABSTRACT:
Compounds are described of the formula ##STR1## wherein R.sub.1 represents a formyl or nitrile group or a group OCH.sub.2 A where A represents hydroxy, C.sub.1-4 alkoxy or D(CH.sub.2).sub.n NR.sub.7 R.sub.8 (where R.sub.7 and R.sub.8 independently represent hydrogen or C.sub.1-4 alkyl and n is 2 or 3);
REFERENCES:
patent: 3923818 (1975-12-01), Bossert et al.
patent: 4307103 (1981-12-01), Sato et al.
patent: 4492703 (1985-01-01), Goldmann et al.
patent: 4801599 (1989-01-01), Semeraro et al.
patent: 4806533 (1989-02-01), Semeraro et al.
Rahwan, R. et al., Annual Reports in Medicinal Chemistry 16 (1981) pp. 257-268.
Thomas G. et al., J. Cardiovascular Pharm. 6, pp. 1170-1176 (1984).
Borthwick Alan D.
Gaviraghi Giovanni
Micheli Dino
Pieraccioli Daniele
Semeraro Claudio
Fan Jane T.
Glaxo S.p.A
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