1,4-dihydropyridine derivatives, and pharmaceutical compositions

Details 1,4-dihydropyridine derivatives, and pharmaceutical compositions 1,4-dihydropyridine derivatives, and pharmaceutical compositions

1985-12-09

1988-07-12

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514269, 514274, 514309, 514312, 514335, 514336, 514342, 544238, 544333, 544405, 546147, 546170, 546263, 546283, 546284, C07D40112, C07D40712, C07D40912, A61K 31455

Patent

active

047570717

ABSTRACT:
2,6-Dimethyl-4-(2- or 3-substituted phenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diesters, having vasodilating and blood pressure lowering effects, in the ester moiety at the 3-position of which a heterocyclic group is linked to an alkylene group through an ester bond (carbonyloxy group). The diesters are used for treatment of cardiac diseases, cerebrovascular diseases and hypertension.

REFERENCES:
patent: 3574843 (1971-04-01), Bossert et al.
patent: 3799934 (1974-03-01), Meyer et al.
patent: 4044141 (1977-08-01), Bossert et al.
patent: 4239893 (1980-12-01), Pigerol et al.
patent: 4258042 (1981-03-01), Loev et al.
patent: 4264611 (1981-04-01), Berntsson
patent: 4317768 (1982-03-01), Pigerol et al.

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