Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-04
1995-02-14
Dentz, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514314, 514321, 514332, 514336, 514338, 514339, 514356, 546147, 546174, 546263, 546270, 546271, 546273, 546284, 546321, A61K 3144, C07D21190
Patent
active
053896440
ABSTRACT:
The compounds are 2,4-disubstituted 3-ethoxycarbonyl 5-methoxycarbonyl 6-methyl 1,4-dihydropyridines in their dextrorotatory form, useful to potentiate the activity of cytotoxic agents and to increase the sensitivity of tumor cells to antitumor agents.
A compound disclosed is d-2-{[2-(2-(N-p-nitrobenzylamino)ethoxy)ethoxy]methyl}-4-(2,3-dichlorophen yl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine.
REFERENCES:
patent: 4870091 (1989-09-01), Peglion et al.
Aasssi Ghanem
Guilbaud Nicolas
Kraus-Berthier Laurence
Peglion Jean-Louis
Pierre Alain
Adir et Compagnie
Dentz Bernard
Hueschen Gordon W.
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