1,4-dihydro-2-(4-[benzimidazol-l-yl]phenyl)-pyridines as platele

Details 1,4-dihydro-2-(4-[benzimidazol-l-yl]phenyl)-pyridines as platele 1,4-dihydro-2-(4-[benzimidazol-l-yl]phenyl)-pyridines as platele

1990-05-01

1991-11-05

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546271, 546118, 546121, 546255, 546256, 546257, 544262, C07D40110, A61K 31415

Patent

active

050632370

ABSTRACT:
Platelet activating factor antagonists of formula (I): ##STR1## wherein R is phenyl or phenyl substituted by one or more substituents selected from nitro, halo, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, aryl(C.sub.1 -C.sub.4)alkoxy, fluoro(C.sub.1 -C.sub.4)alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulphonyl, hydroxy, trifluoromethyl and cyano, or is phenyl fused to a dioxole ring;

REFERENCES:
patent: 3971791 (1976-07-01), Meyer
patent: 4285955 (1981-08-01), Wehinger et al.
patent: 4414213 (1983-11-01), Poindexter et al.
patent: 4788205 (1988-11-01), Cooper et al.
patent: 4820842 (1989-04-01), Anderson et al.

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