Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-10-15
1987-01-06
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
544101, C07D49804, C07D51304
Patent
active
046347666
ABSTRACT:
Compounds of the Formula I: ##STR1## are inhibitors of the mammalian 5-lipoxygenase enzyme system of the arachidonic acid cascade. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders and inflammation.
REFERENCES:
patent: 3746707 (1973-07-01), Gulbenk et al.
patent: 3845044 (1974-10-01), Tong
patent: 4552874 (1985-11-01), Mardin et al.
Carter, Chemical Abstracts, vol. 87, (1977), 152146m.
Cheeseman et al, Tetrahedron, vol. 36, (1980), pp. 2681-2683.
Okafor, J. Het. Chem., vol. 18, (1981), pp. 405-407.
Journal of Medicinal Chemistry, 1983, pp. 564-569; W. S. Saari et al.
Carter et al., Tetrahedron, vol. 33(8), (1977), pp. 827-832.
Atkinson Joseph G.
Belanger Patrice C.
Guindon Yvan
Rokach Joshua
Ginsburg Paul H.
Lopez Gabriel
Merck Frosst Canada Inc.
Pfeiffer Hesna J.
Raymond Richard L.
LandOfFree
1,4-diaza-phenothiazines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1,4-diaza-phenothiazines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,4-diaza-phenothiazines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-684764