1,4-diamino-5-chloro-2-nitrobenzene derivatives, processes for t

Details 1,4-diamino-5-chloro-2-nitrobenzene derivatives, processes for t 1,4-diamino-5-chloro-2-nitrobenzene derivatives, processes for t

1986-02-26

1987-11-03

Warren, Charles F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

8407, 8415, C07C 8760, A61K 713

Patent

active

047044748

ABSTRACT:
New 1,4-diamino-5-chloro-2-nitrobenzene derivatives are disclosed of the formula I ##STR1## Wherein R.sup.1 and R.sup.2 are the same or different and are each hydrogen, 2-hydroxyethyl or 2,3-dihydroxypropyl, with the proviso, that at least one of said R.sup.1 and R.sup.2 is 2,3-dihydroxypropyl, along with processes for their production, as well as hair coloring compositions containing the same and methods of coloring hair. The compounds are red- to violet-coloring direct dyes, and are readily soluble in water, with favorable toxicological characteristics.

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J. C. Johnson, "Hair Dyes" Noyes Corp. Park Ridge (USA) (1973) pp. 1-91, 113-139.
E. Saragin, "Cosmetics", Science Technology (1957) Interscience Publishers Inc., New York, pp. 503-515.
H. Janistyn, "Handbuch der Kosmetica und Reischstoffe" (1973) pp. 378-406.
Ames, B. N. et al, "Methods for Detecting Carcinogens and Mutagens with Salmonella Mammalian-Microsome Mutagenicity Test", Mutation Research vol. 31, pp. 347-364 (1975).
Balsam, M. S. et al, Cosmetics, Science and Technology, vol. 2 p. 297 (1972).

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