Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-11-19
1983-12-13
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544383, 544387, 544398, 544399, A61k 31495, C07D29500
Patent
active
044204825
ABSTRACT:
The present invention concerns compounds of the general formula ##STR1## wherein X represents a direct linkage or a linear or branched oxyalkyl group containing one or more carbon atoms, as well as pharmaceutically acceptable salts of such compounds wherein X represents an oxyalkyl group, methods for their preparation by reaction of either piperazine or of its 1,4-bis-hydroxyalkyl derivatives with activated derivatives of acetylsalicylic acid such as halogenides, symmetric or mixed anhydrides, or with a haloalkylester of acetylsalicylic acid, and related pharmaceutical compositions having use as antipyretic, analgesic, anti-inflammatory and anti-histaminic agents.
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Carminati Giovanni M.
Milani Carlo
Sovera Attilio
Daus Donald G.
Schneider Walter H.
Selvi & C. S.p.A.
Turnipseed James H.
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