1,4-benzodioxine and 1,4-benzodioxine derivatives and production

Details 1,4-benzodioxine and 1,4-benzodioxine derivatives and production 1,4-benzodioxine and 1,4-benzodioxine derivatives and production

1985-10-22

1986-06-17

Siegel, Alan

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549362, C07D40900, C07D31914, A61K 3138

Patent

active

045957673

ABSTRACT:
Highly safe new diuretics, i.e., 1,4-benzodioxane and 1,4-benzodioxine derivatives having potent antihypertensive activity but no or little uricesuric activity, which can be administered to human orally, intravenously, or hypodermically at a respective daily dosage of 0.1-2 mg/kg, 0.005-0.1 mg/kg, or 0.02-0.4 mg/kg.

REFERENCES:
patent: 4097582 (1978-06-01), Briet et al.
patent: 4177286 (1979-12-01), Doria et al.
patent: 4205076 (1980-05-01), Durham et al.
patent: 4517184 (1985-05-01), Habicht et al.
patent: 4545993 (1985-10-01), Okamoto et al.

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