Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-06-17
1993-01-05
Friedman, S. J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
A61U 3155
Patent
active
051770717
ABSTRACT:
Pharmaceutical compositions containing 6-membered heterocyclic rings are disclosed which are useful in the treatment of panic disorder or anxiety disorder.
REFERENCES:
patent: 4820834 (1989-04-01), Evan et al.
Bradwejn, et al., Enhanced Sensitivity to Cholecystokinin Tetrapeptide in Panic Disorder, Soc. Neurosci. Abstr. 14(1), p. 291, (1988).
de Montigny, Cholecystokinin Tetrapeptide Induces Panic Attacks in Healthy Volunteers, Soc. Neurosci. Abstr. 14(1), p. 291 (1988).
Bradwejn, et al., Benzodiazepines Antagonize Cholecystokinin--Induced Activation of Rat. hippocampal. Nature 312, p. 22, (1984).
de Montigny, Cholecystokinin Tetrapeptide Induces Panic-like Attacks in Healthy Volunteers, Arch. Gen. Psychiatry, 46, (1989).
Dourish, et al., Morphine Induced Analgesia in the Rat Paw Pressure Test is Blocked by CCK and Enhanced by the CCK Antagonist MK-329, Eur. Jour. Pharm. 147, No. 3, pp. 469-472, (1988).
Bouthillier, et al., Long-term Benzodiazepine Treatment Reduces Neuronal Responsiveness to Cholecystokinin: an Electrophysiological Study in the Rat, Eur. Jour. Pharm. 151, No. 1, pp. 135-138, (1988).
Bock Mark G.
Evans Ben E.
Freidinger Roger M.
Daniel Mark R.
DiPrima Joseph F.
Friedman S. J.
Merck & Co. , Inc.
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