1-(4-Aminobenzyl)-2,3-dioxopiperazine derivatives, acid addition

Details 1-(4-Aminobenzyl)-2,3-dioxopiperazine derivatives, acid addition 1-(4-Aminobenzyl)-2,3-dioxopiperazine derivatives, acid addition

1982-02-12

1984-10-16

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544395, 544399, 544404, C07D24104

Patent

active

044776667

ABSTRACT:
A 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative represented by the formula: ##STR1## and an acid addition salt thereof have excellent carcinostatic activity but a low toxicity. Therefore, said compounds are useful as medicines and also as intermediates.

REFERENCES:
patent: 4110327 (1978-08-01), Saikawa et al.
Hori, et al., Chem. Pharm. Bull., 29, (3), 684-698, (1981).
Hori, et al., Chem. Pharm. Bull., 29, (6), 1594-1605, (1981).

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