Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-03-29
1976-05-04
Hines, Robert V.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260239B, 2602471R, 260268R, 26029373, 260307A, 260309, 260348R, 260455R, 260456A, 260470, 26050119, 260516, 2605705C, 2605705P, 260573, 424248, 424250, 424267, 424273, 424316, 424330, C07C 9122
Patent
active
039548716
ABSTRACT:
The new amino-alcohols according to the invention are represented by the formula ##SPC1##
Wherein: R.sub.1 represents a RS, RSO or RSO.sub.2 group in which R is a linear or branched alkyl group (C.sub.1 -C.sub.10), an acetyl radical or hydrogen; R.sub.2 and R.sub.3, which may be identical or different, represent a halogen atom or an alkyl (C.sub.1 -C.sub.3), amino, alkylamino (C.sub.1 -C.sub.4), acylamino, nitro, carboxy, carbalkoxy, trifluoromethyl, alkoxy (C.sub.1 -C.sub.4) or alkylthio (C.sub.1 -C.sub.4) radical; R.sub.4 represents hydrogen or a linear or branched alkyl radical containing 1 - 4 carbon atoms; R.sub.5 and R.sub.6, which may be identical or different, represent hydrogen, a substituted or not, linear or branched alkyl (C.sub.1 -C.sub.16) radical, a cycloalkyl (C.sub.5 -C.sub.6) radical, an alkynyl (C.sub.3 -C.sub.4) radical, an alkenyl (C.sub.3 -C.sub.4) radical or a heterocycle of the kind piperidine, morpholine, pyridine or pyridimine, R.sub.5 and R.sub.6 can also form with adjacent nitrogen atom a heterocyclic radical, substituted or not; one of said R.sub.2 and R.sub.3 can be a hydrogen atom or can be both a hydrogen atom provided that simultaneously R is a lower alkyl (C.sub.1 -C.sub.3) radical in the group RS, R.sub.4 and R.sub.5 are hydrogen atoms and R.sub.6 is an isopropyl or t-butyl radical or if simultaneously R is a methyl radical in the group RSO.sub.2, R.sub.4 and R.sub.5 are hydrogen atoms and R.sub.6 is an isopropyl radical.
When R.sub.5 and R.sub.6 represent an alkyl, the latter can be substituted by amino, alkylamino, hydroxy, alkoxy, phenoxy, substituted phenoxy, phenyl, substituted phenyl radical or a heterocycle such as piperidino or morpholino.
REFERENCES:
buu-Hoi et al., "Chemical Abstracts," Vol. 73, p. 344, Section No. 109490t, (1970).
Buu-Hoi Nguyen Phuc
Gillet Claude
Jacques Guy D.
Lambelin Georges E.
Roba Joseph L.
Continental Pharma
Hines Robert V.
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