1-(4'-alkylamido)-2 '{1[n-(alkyl)imino]-ethyl}-phenoxy-3-alkylam

Details 1-(4'-alkylamido)-2 '{1[n-(alkyl)imino]-ethyl}-phenoxy-3-alkylam 1-(4'-alkylamido)-2 '{1[n-(alkyl)imino]-ethyl}-phenoxy-3-alkylam

1984-06-19

1986-04-01

Shaver, Paul F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C10338

Patent

active

045799709

ABSTRACT:
The present invention concerns new (R)-, (S)- and (R,S)-1-(4'-alkylamido)-2'-{1-[N-(alkyl)imino]ethyl}phenoxy-3-alklyamino-2 -propanols having the general formula ##STR1## wherein R means a straight or branched C.sub.1 -C.sub.4 -alkyl group, especially the n-propyl group, and R.sub.1 means hydrogen or a straight or branched C.sub.1 -C.sub.4 -alkyl group, especially the isopropyl group, which compounds are useful intermediates when preparing the pharmacologically active (R)-, (S)- and (R,S)-1-(4'-alkylamido-2'-acetyl)phenoxy-3-alkylamino-2-propanols of the formula ##STR2## wherein R and R.sub.1 have the meaning given above.

REFERENCES:
patent: 3284490 (1966-11-01), Baltzly et al.
patent: 3634511 (1972-01-01), Howe et al.
patent: 3726919 (1973-04-01), Wooldridge et al.
patent: 3875149 (1975-04-01), Wooldridge et al.

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