1-(3-Vinylphenyl)-1-phenylhydrocarbons and method for producing

Details 1-(3-Vinylphenyl)-1-phenylhydrocarbons and method for producing 1-(3-Vinylphenyl)-1-phenylhydrocarbons and method for producing

1988-03-09

1989-04-18

Garvin, Patrick P.

Chemistry of hydrocarbon compounds

Compound or reaction product mixture

Aromatic

C07C 1516

Patent

active

048229342

ABSTRACT:
1-(3-Vinylphenyl)-1-phenylhydrocarbons and method for producing the same. The invention further relates to 1-(3-vinylphenyl)-1-phenylethane which is used for preparing the former compound. The 1-(3-vinylphenyl)-1-phenylethylene is used as a new intermediate for preparing .alpha.-(3-benzoylphenyl)propionic acid (tradename: ketoprofen) through .alpha.-3-(1-phenylethenyl)phenyl)propionic acid or its alkyl ester. The ketroprofen is a useful medicine for the relief of pain and inflammation.

REFERENCES:
patent: 4618914 (1986-10-01), Sato et al.
patent: 4761508 (1988-08-01), Shimizu et al.
Kluiber, R. W., "Equilibrium of Para-Substituted Styrenes to Produce P-Xylenes", Journal of Organic Chemistry, 30(6), pp. 2037-2041 (1965).

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