Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-05-23
1978-06-20
Siegel, A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D33324
Patent
active
040961559
ABSTRACT:
There are provided substituted 1,3-dithiolane compounds and a method for preparing the same. Said 1,3-dithiolane compounds are useful intermediates in the preparation of tetrahydro-7-oxobenzo[b]thien-4-ylureas and tetrahydro-4-oxo-1-naphthylureas which are known animal growth-promoting agents, which thiolanes are represented by the formula: ##STR1## wherein R.sub.1 is a member selected from the group consisting of 2-thienyl and phenyl; R.sub.2 is a member selected from the group consisting of ##STR2## wherein X is chlorine or bromine; R.sub.3 and R.sub.4 are each members selected from the group consisting of hydrogen and methyl; and when R.sub.1 and R.sub.2 are taken together with the carbon atom to which they are attached they represent a bicyclic moiety selected from the group consisting of ##STR3## wherein the carbon atom of said bicyclic moiety marked with an asterisk is also part of the 1,3-dithiolane ring; U is a moiety selected from the group consisting of ##STR4## and when U is ##STR5## said compounds are the racemic mixtures and the optical isomers thereof.
REFERENCES:
patent: 3803172 (1974-04-01), Van der Wal
Eur. J. Med. Chem.-Chim. Ther. 1975 10(1), 14-18 (Fr.).
Asato Goro
Gastrock William Henry
American Cyanamid Company
Kline Harry H.
Siegel A.
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