1,3-Disubstituted 3-aroylpropanes and process for the preparatio

Details 1,3-Disubstituted 3-aroylpropanes and process for the preparatio 1,3-Disubstituted 3-aroylpropanes and process for the preparatio

1973-04-18

1976-04-20

Gallagher, R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260246B, 2602472A, 2602472B, 2602475R, 2602475F, 2602475G, 260268R, 26029364, 26029371, 26029376, 26029378, 2602938, 26032643, 2603265J, 260477, 260465E, 260561R, 260490, 2605706, 2605707, 2605709, 260268H, 2605708R, 424250, C07D29510, C07D29512

Patent

active

039519783

ABSTRACT:
1,3-Disubstituted-3-aroylpropanes of the formula: ##EQU1## and their salts, in which Ar represents an aryl residue unsubstituted or substituted by halogen, polyhalogeno alkyl or lower alkoxy; R.sup.1 represents an hydroxy, acyloxy, carbamoyloxy, alkylcarbamoyloxy, dialkylcarbamoyloxy, aroyloxy, alkoxy, aryloxy, or cyano group or an amino group of the formula: ##EQU2## which can be the residue of a secondary amine, a tertiary amine, or of a heterocyclic amine; and ##EQU3## represents the residue of a secondary amine, a tertiary amine, or of a heterocyclic amine, have interesting properties as analgesic agents, anti-arrhythmic agents, and central nervous depressants.

REFERENCES:
patent: 2997472 (1961-08-01), Janssen
patent: 3210368 (1965-10-01), Huebner
patent: 3732229 (1973-05-01), Bysouth et al.

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