1,3-Dioxan-5-yl-hexenoic acids

Details 1,3-Dioxan-5-yl-hexenoic acids 1,3-Dioxan-5-yl-hexenoic acids

1988-07-12

1990-01-23

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31906

Patent

active

048959634

ABSTRACT:
The invention provides a novel group of 4(Z)-6-([2,4,5-cis]-2-alkyl-4-o-hydroxyphenyl-1,3-dioxan-5-yl)hexenoic acids of formula I wherein R is branched alkyl or 3-5 carbon atoms and one of X and Y is hydrogen or fluoro and the other is hydrogen, and their pharmaceutically acceptable salts; together with their pharmaceutical compositions for use in treating a variety of disease conditions. Also provided are methods for the manufacture of the novel compounds. A representative compound is that in which R is t-butyl and X and Y are both hydrogen.

REFERENCES:
patent: 4567197 (1986-01-01), Brewster et al.

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