1,3-Diaryl-pyrazol-4-acrylic acid and derivatives

Details 1,3-Diaryl-pyrazol-4-acrylic acid and derivatives 1,3-Diaryl-pyrazol-4-acrylic acid and derivatives

1971-11-30

1978-06-13

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260295R, 260295AM, 2602955R, 2602955A, 260296R, 260296D, 424263, 424273P, C07D23112

Patent

active

040950255

ABSTRACT:
The invention concerns diarylpyrazole lower alkanoic acids and derivatives which are pharmacologically efficacious as anti-inflammatory agents. The said compounds can be represented by the formula ##STR1## in which one of D, E, F and G represents hydrogen, one is a lower aliphatic acid radical or derivative thereof and the remaining two of D, E, F and G are aryl or heteroaryl radicals.

REFERENCES:
Nabeya et al. J. Org. Chem. vol. 35, pp. 2015-2021, (1970, Jun., 1970).
Moritani et al. J. Org. Chem. vol. 34, pp. 670-675, (1969).
Bettinetti et al. Gaz. Chim. Ital. vol. 94, pp. 91-108, (1964).
Beilsteins Handbuch der Organischen Chemie 4th ed. vol. 25, pp. 123-124, Berlin, Springer, 1936.
Jones et al. J. Amer. Chem. Soc. vol. 75, p. 4052 relied on, (1953).
Lukes Collection Czechoslov. Chem. Communs. vol. 19, pp. 1205-1214, (1954).

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