1,3-Diamino-2-hydroxypropane pro-drug derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S304000, C546S314000, C548S190000, C548S200000, C514S352000, C514S354000, C514S370000

Reexamination Certificate

active

10657567

ABSTRACT:
The present invention relates to compounds of formula (AA) (I) and (X):useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

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