1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular h

Details 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular h 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular h

1997-11-21

1998-09-15

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549 79, 549497, 549501, 548203, 548204, 548235, 548236, C07D33304, C07D33328, C07D30734

Patent

active

058081011

ABSTRACT:
Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, are capable of lowering intraocular pressure in the eye of a mammal.

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patent: 5151440 (1992-09-01), Gluchowski
patent: 5369127 (1994-11-01), Burk et al.
Bito, L. Z., Applied Pharmacology in the Medical Treatment of Glaucomas Drance, S.M. and Neufeld, A.H. eds., New York, Grune & Stratton, 1984, pp. 477-505.
Journal of Medicinal Chemistry 1975, vol. 18, pp. 1094-1098 by Bender et al.
Bito, L. Z., Biological Protection with Prostaglandins, Cohen, M.M., ed., Boca Raton Fla. CRC Press Inc., 1985, pp. 231-252.
M.S. Starr, Exp. Eye Res. 11, 170-177 (1971).
Barreiro et al., J. Chem Res. Symop., 7, pp. 220-221 (1985), (C.A. 104: 1943c, 1986).
Lupi et al., CA 114:82208, 1991 (Registry No. 132113-56-5).

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