1,3-benzenedimethanamines useful as central nervous system activ

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514654, 514655, 558422, 560 18, 560 34, 560 37, 560 42, 562426, 562439, 562442, 562451, 564237, 564368, 564388, A61K 31135, A61K 31155, C07C21128, C07C27912

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054280656

ABSTRACT:
Pharmaceutical compounds of the formula: ##STR1## R.sup.1 to R.sup.8 are each hydrogen or C.sub.1-4 alkyl, m, n and p are each 0, 1, or 2, q is 0, 1, 2 or 3, X and Z are each C.sub.1-4 alkyl, C.sub.1-4 alkoxy, hydroxy, nitro, cyano, halo, trihalomethyl, carboxy, C.sub.1-4 alkoxy-carbonyl or phenyl, and in addition z, together with the phenyl ring to which it is attached, can be: ##STR2## Y is --O--, --S-- or --CH.sub.2 --, V is --(CH.sub.2).sub.r -- or --(CH.sub.2).sub.r S-- where r is 1 to 15, and W is hydrogen or optionally substituted phenyl; and salts thereof.

REFERENCES:
patent: 3280097 (1966-10-01), Cizek
patent: 3755445 (1973-08-01), Manschke et al.
Merck Index, 8699 (11th Ed., 1989), p. 1379.

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