1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic ureas useful as HI

Details 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic ureas useful as HI 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic ureas useful as HI

1997-11-07

1999-08-03

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540489, 540492, A01N 4362, C07D27302, C07D24300

Patent

active

059325704

ABSTRACT:
The present invention relates to compounds of formulae I and II: ##STR1## or pharmaceutically acceptable salt forms or prodrugs thereof, which are useful as inhibitors of HIV protease, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

REFERENCES:
patent: 5521161 (1996-05-01), Malley et al.
patent: 5532357 (1996-07-01), Rodgers et al.
patent: 5610294 (1997-03-01), Lam et al.
Vila et al, Lancet 1997, 350 635-636, "Absence of viral rebound after treatment of HIV-infected patients with didanosine and hydroxycarbamide."

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