1,3,5-trithiane derivatives and pharmaceutical compositions ther

Details 1,3,5-trithiane derivatives and pharmaceutical compositions ther 1,3,5-trithiane derivatives and pharmaceutical compositions ther

1988-10-17

1991-09-03

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549 19, A61K 31385, C07D34100

Patent

active

050455621

ABSTRACT:
1,3,5-trithiane derivatives represented by the formula (I) ##STR1## wherein the substituents are defined herein, are disclosed. The trithiane derivatives and their compositions are useful as anti-arteriosclerotic or anti-hyperlipemic agents.

REFERENCES:
patent: 3525751 (1970-08-01), Fried
patent: 3792043 (1974-02-01), Chang
European Search Report, Appln. No. 87110180.4-2110, Feb. 2, 1990.
Chemical Abstracts, C. Paul Bianchi, 1-Pharmacodynamics, Jun. 19, 1978.
Chemical Abstracts, C. Paul Bianchi, 1-Pharmacology, Apr. 26, 1982.
M. Mikoxajczyk et al., A New General Synthesis of Ketene Thioacetals, Tetrahydro Letters-No. 31, pp. 2731-2734, 1976.
Mikolajczyk et al., Tetrahedron (34), pp. 3081-3088 (1978).

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