1,3,5(10),6,8,14-19-Nor-pregnahexaenes, their use as anti-psoria

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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26039745, C07J 700

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active

041721322

ABSTRACT:
1,3,5(10),6,8,14-19 Nor-pregnahexaene-20-ones exhibit anti-mitotic activity with minimal or no hormonal activity. They are particularly useful in the treatment and control of psoriasis when applied topically, a preferred anti-psoriatic compound being 16.alpha.-methyl-1,3,5(10),6,8,14-19-nor-pregnahexaene-3,17.alpha.,21-trio l-20-one 21-acetate.

REFERENCES:
patent: 3182057 (1965-05-01), Heller et al.
patent: 3182075 (1965-05-01), Heller et al.

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