1,3,4-Thiadiazole derivatives and pharmaceutical preparations us

Details 1,3,4-Thiadiazole derivatives and pharmaceutical preparations us 1,3,4-Thiadiazole derivatives and pharmaceutical preparations us

1985-11-19

1988-04-19

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514269, 514317, 514318, 514326, 514340, 514363, 514422, 540597, 540601, 540603, 544316, 546192, 546193, 546194, 546209, 546277, 548141, 548518, A61K 3138, A61K 3141, C07D28512

Patent

active

047389605

ABSTRACT:
1,3,4-Thiadiazole derivatives corresponding to the general formula I ##STR1## which constitute highly effective inhibitors for histamine-H.sub.2 receptors are described. These compounds in addition have a cytoprotective action.

REFERENCES:
patent: 4440933 (1984-04-01), Montzka
patent: 4447440 (1984-05-01), Busse
patent: 4578471 (1986-03-01), Crenshaw et al.
patent: 4587254 (1986-05-01), Toyofuku et al.
patent: 4600779 (1986-07-01), Crenshaw et al.
Morrison and Boyd, Organic Chemistry, 5/74, pp. 738-740.
Noller, Chemistry of Organic Chemistry, 1965, p. 512.
Chemical Abstracts, 102:113506n (JP196,879/1984).

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