1-3-(4-Fluorobenzoyl)propyl-4-substituted phenoxy ethyl piperazi

Details 1-3-(4-Fluorobenzoyl)propyl-4-substituted phenoxy ethyl piperazi 1-3-(4-Fluorobenzoyl)propyl-4-substituted phenoxy ethyl piperazi

1974-03-05

1976-06-29

Narcavage, Joseph A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424250, C07D29508

Patent

active

039667359

ABSTRACT:
Piperazine derivatives having the following general formula ##EQU1## in which n is 2 or 3, X is an oxy or thio radical, and A and B are each a radical of the group consisting of phenyl radicals containing at most three substituents of the group consisting of nitro, trifluoromethyl, halogen, cyano, and alkyl, alkoxy, alkylthio, acyl, and alkylsulfonyl radicals containing at most 6 carbon atoms, and similar cycloalkyl and cycloalkylalkyl radicals, their acid addition salts, processes for their production, and pharmaceutical compositions containing the same. The compounds have a very favorable action on the central nervous system and are effective agents for the treatment of anxiety states, psychoses, emotional disturbances, aggressive tendencies, and can be used generally for the treatment of psychiatrically disturbed and psychoneurotic patients.

REFERENCES:
patent: 2695293 (1954-11-01), Swain
patent: 2695295 (1954-11-01), Swain
patent: 3000892 (1961-09-01), Janssen
patent: 3637704 (1972-01-01), Umemoto

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