1,3,2-benzodithiazole-1-oxide compounds

Details 1,3,2-benzodithiazole-1-oxide compounds 1,3,2-benzodithiazole-1-oxide compounds

1991-05-07

1992-08-18

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Silicon containing doai

514360, 548110, 548123, C07D28501, A61K 3141

Patent

active

051400189

ABSTRACT:
Novel 1,3,2-benzodithiazole-1-oxides of formula (I) ##STR1## and their pharmaceutically acceptable salts are disclosed, wherein R.sup.1 is a substituent on the 4-, 5-, 6- or 7-position of the benzodithiazole nucleus selected from the group consisting of hydrogen, (C.sub.1 -C.sub.4)alkyl, halogen, halo(C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, and nitro; and

REFERENCES:
patent: 3490893 (1970-01-01), Ahle et al.
patent: 4911754 (1990-03-01), Hunt et al.
patent: 4988809 (1991-01-01), Seidel et al.
Massimo et al., Il Farmaco, 45(4):439-446 (1990).
Chen et al., Synthesis of 5-Methyl-1,3,2-benzodithiazoles, J. Heterocyclic Chem., 16:183 (1979).

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