1,25-dihydroxyvitamin D.sub.2 compounds

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07J 900

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047691816

ABSTRACT:
The invention is directed to the preparation of hydroxylated compounds of the vitamin D.sub.2 series and specifically to a process for synthesizing 1.alpha.,25-dihydroxyvitamin D.sub.2, 1.beta.,25-dihydroxyvitamin D.sub.2, their corresponding 5,6-trans isomers and the C-24 epimers of these compounds.
The hydroxylated vitamin D.sub.2 compounds obtained exhibit vitamin D-like activity and can be substituted for vitamin D.sub.3 or various of its known metabolites where such compounds are applied.

REFERENCES:
patent: 4225596 (1980-09-01), DeLuca
patent: 4260549 (1981-04-01), DeLuca et al.

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