Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1983-10-03
1985-01-22
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
2603972, A61K 3159
Patent
active
044951817
ABSTRACT:
Novel biologically active metabolites of vitamin D.sub.3, 1,23,25-trihydroxy-24-oxo-vitamin D.sub.3 (1,23,25(OH).sub.3 -24-oxo-D.sub.3); and 1,25,-Dihydroxy-24-oxo-vitamin D.sub.3 (1,25(OH).sub.2 -24-oxo-D.sub.3). Also the method of preparing these novel metabolites of vitamin D.sub.3. The use of these compounds in humans for the treatment of disease states involving calcium homeostatic disorders by the administration of an effective amount of said compounds.
REFERENCES:
Yamada et al., "Jour. Biological Chem.", vol. 258, No. 1, Jan. 10, 1983, pp. 457-463.
Mayer Eberhard
Norman Anthony W.
Mueth Joseph E.
Roberts Elbert L.
The Regents of the University of California
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