1-[2-(phenylmethyl) phenyl]piperazines as antidepressants

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544395, A61K 31495, C07D29502

Patent

active

048596752

ABSTRACT:
An 1-[2-(phenylmethyl)phenyl]piperazine of the formula (I), ##STR1## or a pharmaceutically acceptable acid addition salt thereof, wherein R.sub.1 is hydrogen, C.sub.1-4 alkyl or halogen, R.sub.2 is hydrogen, C.sub.1-4 alkyl, halogen or C.sub.1-4 alkoxy and R.sub.3 is hydrogen or methyl.
such compounds are useful as antidepressive agents.

REFERENCES:
patent: 4194049 (1980-03-01), Field et al.
Wolf Dieter Zahler et al, Chem. Ber. 96, 765(1963).
Gassman et al, J.A.C.S. 100(24), 7600(1978).

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