1-(2-Naphthyl)-2,3-butadien-1-ols

Details 1-(2-Naphthyl)-2,3-butadien-1-ols 1-(2-Naphthyl)-2,3-butadien-1-ols

1973-10-01

1976-07-13

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239B, 260247, 2602471R, 26029362, 2603265C, 2603265S, 2603459, 2603472, 2603478, 260456R, 260456P, 26050115, 2605676M, 2605705R, 2605705CA, 2605705S, 260609F, 260618D, 260618E, 260618F, 424337, 424341, 424343, C07C 4320, C07C 3306, C07C14900

Patent

active

039694151

ABSTRACT:
Disclosed are compounds of the class 1-naphthyl-2,3-butadien-1-ol e.g. 2-(6'-methoxy-2-naphthyl)-3,4-pentadien-2-ol, which are useful by reason of their pharmacological activity in animals, e.g. as anti-inflammatory agents. Said compounds can be readily prepared by reduction of a corresponding 4-substituted-1-naphthyl-2-butyne-1-ol with a complex hydride such as lithium aluminium hydride.

REFERENCES:
patent: 3562336 (1971-02-01), Nelson
patent: 3626012 (1971-12-01), Fried et al.
patent: 3641161 (1972-02-01), Fried et al.
patent: 3651148 (1972-03-01), Nelson
Cherkasov et al., Chem. Abstract, 66, 7576 on, (1967).
Petrov et al., Chem. Abstract, 54, 8677h.

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