1-[(-2-Mercaptocycloalkyl)carbonyl]-L-proline derivatives, the p

Details 1-[(-2-Mercaptocycloalkyl)carbonyl]-L-proline derivatives, the p 1-[(-2-Mercaptocycloalkyl)carbonyl]-L-proline derivatives, the p

1981-03-03

1983-05-24

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

548533, A61K 3140, C07D20716

Patent

active

043850626

ABSTRACT:
1-[(2-Mercaptocycloalkyl)carbonyl]-L-proline derivatives of the formula ##STR1## wherein R, R.sup.1, and R.sup.2, each independently, represent hydrogen or a (C.sub.1 -C.sub.4)alkyl radical, n represents the integer 1, 2, 3, 4, or 5, and, in each of the n (CR'.sub.2) groups, R' represents hydrogen or (C.sub.1 -C.sub.4)alkyl, are described as well as the process for their manufacture, the intermediates for their synthesis and their use as antihypertensive agents.

REFERENCES:
patent: 4332725 (1982-06-01), Fischer et al.
Ondetti et al.; Science; vol. 196; pp. 441-444 (1977).

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