Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1985-03-14
1989-03-28
Reamer, James H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
564254, 564255, 564256, 564265, A61K 3115
Patent
active
048164879
ABSTRACT:
New 1-(2-hydroxylaryl)-alkane-1-on-oximes, procedure for their preparation, and their applicability to pharmaceutical preparations. One purpose is to develop 1-(2-hydroxyaryl)-alkane-1-on-oximes with desirable pharmacological properties. The new compounds of Formula I ##STR1## are characterised by pharmacologically valuable properties, in particular by anti-asthmatic, anti-anaphylactic, antiphlogistic, antihypertensive, spasmolytic, antirheumatic, and antithrombotic, potentials and are applicable in human and veterinary medicine to therapy of asthma bronchiale and other allergic diseases, various kinds of inflammatory and rheumatic diseases, and thrombosis.
REFERENCES:
patent: 3579556 (1971-05-01), Briggs et al.
patent: 4141995 (1979-02-01), Saunders et al.
patent: 4678810 (1987-07-01), Danree
Krauch, Helmut et al, Organic Name Reactions (1964) John Wiley & Sons, Publ. At p. 491.
Synthesis vol. 1 (Jan. 1982) pp. 68-69; Georg Thieme Verlag, Stuttgart, New York; Table 1, Example 28.
Beger Joerg
Binte, deceased Hans-Joachim
Grupe Renate
Kuehn Hartmut
Rapoport Samuel M.
Humboldt--Universitaet zu Berlin
Reamer James H.
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