Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1977-04-20
1979-04-10
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242484, 42424857, 544173, 544174, 544378, 544391, 544396, 544398, 544401, 544402, 544403, A61K 31495, C07D29508
Patent
active
041488970
ABSTRACT:
Novel 1,2-dihydronaphthalene derivatives of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently of each other, are hydrogen, nitro, amino, halogen, or hydroxyl which may be protected, and R.sup.3 is a piperazinyl or morpholino group which may be substituted by lower alkyl, aralkyl, carboxylic acid-derived acyl, lower alkoxycarbonyl-lower alkyl or cycloaminocarbonyl-lower alkyl, and its salts have excellent pharmacological activities such as vasodilator and cerebral blood flow increasing activities.
REFERENCES:
patent: 3845058 (1974-10-01), Lembo et al.
patent: 3886168 (1975-05-01), Himmele et al.
patent: 3919230 (1975-11-01), Hill et al.
patent: 4022791 (1977-05-01), Welch
patent: 4035498 (1977-07-01), Mauvernay et al.
Hirata Minoru
Itoh Katsumi
Miyake Akio
Oka Yoshikazu
Coughlan, Jr. Paul M.
Takeda Chemical Industries Ltd.
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