1,2-Dihydronaphthalene derivatives and pharmaceutical compositio

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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4242484, 42424857, 544173, 544174, 544378, 544391, 544396, 544398, 544401, 544402, 544403, A61K 31495, C07D29508

Patent

active

041488970

ABSTRACT:
Novel 1,2-dihydronaphthalene derivatives of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently of each other, are hydrogen, nitro, amino, halogen, or hydroxyl which may be protected, and R.sup.3 is a piperazinyl or morpholino group which may be substituted by lower alkyl, aralkyl, carboxylic acid-derived acyl, lower alkoxycarbonyl-lower alkyl or cycloaminocarbonyl-lower alkyl, and its salts have excellent pharmacological activities such as vasodilator and cerebral blood flow increasing activities.

REFERENCES:
patent: 3845058 (1974-10-01), Lembo et al.
patent: 3886168 (1975-05-01), Himmele et al.
patent: 3919230 (1975-11-01), Hill et al.
patent: 4022791 (1977-05-01), Welch
patent: 4035498 (1977-07-01), Mauvernay et al.

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