1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones

Details 1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones 1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones

1977-04-28

1979-01-16

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

2602444, 2602433, 548302, 542412, 542415, 542431, 542436, 544 60, 544139, 544370, 424273R, 424246, 42424854, 424250, A61K 31415, C07D47104

Patent

active

041349768

ABSTRACT:
Novel 1,2-dihydro-6-phenyl-1H,4H-imidazo[1,2-a] [1,4]-benzodiazepin-1-ones of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, halogen, nitro and trifluoromethyl, R.sub.1 is selected from the group consisting of hydrogen and halogen, R.sub.2 is selected from the group consisting of hydrogen and methyl and R.sup.3 and R.sup.4 are individually selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, hydroxyalkyl of 1 to 5 carbon atoms, aminoalkyl of 1 to 5 carbon atoms, mono-and di-alkyl-aminoalkyl with each alkyl having 1 to 5 carbon atoms, cycloalkyl of 3 to 8 carbon atoms and mono and di-nuclear aryl or R.sub.3 and R.sub.4 taken together with the nitrogen atom to which they are attached form a saturated heterocycle which may contain a second heteroatom optionally substituted with at least one member of the group consisting of alkyl of 1 to 5 carbon atoms, hydroxyalkyl of 1 to 5 carbon atoms, dialkylphosphinylalkyl with 1 to 5 carbon atoms in the alkyl groups, cycloalkylalkyl with 3 to 6 carbon atoms in the ring and 1 to 5 alkyl carbon atoms, alkenyl of 2 to 5 carbon atoms, phenyl and nitrogen heterocycles and their non-toxic, pharmaceutically acceptable acid addition salts having sedative, hypnotic, anxiolytic, tranquilizing, anticonvulsive and myorelaxant properties and their preparation.

REFERENCES:
patent: 3846443 (1974-11-01), Moffett
patent: 3920687 (1975-11-01), Buzby, Jr. et al.
patent: 3933794 (1976-01-01), Hester, Jr. et al.
Derieg et al., Chem. Abst. 1968, vol. 69, No. 36092v.
Derieg et al., Chem. Abst. 1969, vol. 70, No. 87862z.

Affiliated with

Also associated with

Rating

1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-651956