Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-03-17
1981-05-05
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546119, 546257, 546258, C07D47102, A61K 31415
Patent
active
042658950
ABSTRACT:
1,2-Dihydro-1-R-5-PY-6-Q-3H-pyrazolo[3,4-b]pyridin-3-ones or pharmaceutically-acceptable acid-addition salts thereof, which are useful as cardiotonic agents, are prepared by reacting lower-alkyl 2-halo-5-PY-6-Q-nicotinate with 1-R-hydrazine. Also disclosed are cardiotonic compositions and method for increasing cardiotonic contractility using said compounds or salts.
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patent: 4072746 (1978-02-01), Lesher et al.
patent: 4107315 (1978-08-01), Lesher et al.
C.A., 87, (1977), 39357t, Balicki, et al.
Balicki et al., Acta Poloniae Pharmaceutica, (1976), vol 33 (3), pp. 289-293.
Nantka-Namirski, et al., Pol. J. Pharmacol. Pharm., (1978), vol. 30, pp. 707-712.
Gruett Monte D.
Lesher George Y.
Bair Robert K.
Brust Joseph Paul
Sterling Drug Inc.
Wyatt B. Woodrow
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