1,2-dihydro-2-oxopyridines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546276, A61K 3144, C07D40104

Patent

active

053327500

ABSTRACT:
New 1,2-dihydro-2-oxopyridines of formula I ##STR1## in which R is the radical ##STR2## and R.sup.1 to R.sup.6 and X are as defined herein,
and their salts, have antagonistic properties towards angiotensin II and can be used for the treatment of hypertension, aldosteronism and cardiac insufficiency.

REFERENCES:
patent: 4880804 (1989-11-01), Carini et al.
patent: 5130318 (1992-07-01), Roberts et al.
patent: 5236936 (1993-08-01), Roberts et al.
patent: 5250548 (1993-10-01), Winn et al.
*Zeffren, The Study of Enzyme Mechanism, p. 87, 1974.
*Wade, Jr., Organic Chemistry, p. 349, 1987.
Aumailley et al., FEBS Letters, vol. 291, No. 1, pp. 50-54 (Oct. 1991).
Smith et al., The Journal of Biological Chemistry, vol. 265, No. 21, pp. 12267-12271 (Jul. 25, 1990).

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