1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrah

Details 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrah 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrah

1985-02-04

1986-11-25

Rosen, Sam

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546153, 546155, 546157, 546158, C07D21514, C07D21520

Patent

active

046250344

ABSTRACT:
This invention relates to novel lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic activities. The present new compounds are di- and tetra-hydroquinoline or di- and tetra-hydronapthalene derivatives, more particularly, 1,2-, 1,4-, 5,6-, or 7,8-dihydro; 1,2,3,4-tetrahydro-; 5,8-dihydro-; or 5,6,7,8-tetrahydroquinoline or napthalene derivatives of a compound of the formula: ##STR1## and oxides, quaternary ammonium salts and acid salts thereof; wherein A is CH or N;

REFERENCES:
patent: 4236912 (1980-12-01), Johnston
patent: 4408076 (1983-10-01), Lee
patent: 4444584 (1984-04-01), Serban
patent: 4563526 (1986-01-01), Dewhirst
patent: 4567184 (1986-01-01), Musser, II
patent: 4576949 (1986-03-01), Smith

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