Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing
Patent
1986-11-17
1991-04-30
Shaver, Paul F
Organic compounds -- part of the class 532-570 series
Organic compounds
Heavy metal containing
549206, 514 23, 514189, 514492, 127 29, 127 30, C07F 1500, A01N 4304, A01N 5502, A61K 3128
Patent
active
050119591
ABSTRACT:
The present invention comprises a water-soluble square-planar cis-platinum(II) four-coordinate complex having the formula:
REFERENCES:
patent: 4169846 (1979-10-01), Kidani et al.
patent: 4560781 (1985-12-01), Totani et al.
patent: 4562275 (1985-12-01), Speer et al.
patent: 4565884 (1986-01-01), Andrulis, Jr. et al.
patent: 4575550 (1986-03-01), Totani
patent: 4577038 (1986-03-01), Totani et al.
patent: 4578491 (1986-03-01), Amundsen et al.
patent: 4584316 (1986-04-01), Rosenberg et al.
patent: 4584392 (1986-04-01), Smith et al.
patent: 4594418 (1986-06-01), Speer et al.
patent: 4599352 (1986-07-01), Narayanan et al.
patent: 4614811 (1986-09-01), Gandolfi
patent: 4617189 (1986-10-01), Stockel et al.
patent: 4658047 (1987-04-01), Vishnurajjala
patent: 4658048 (1987-04-01), Totani et al.
patent: 4659849 (1987-04-01), Drobnik et al.
patent: 4661516 (1987-04-01), Brown, et al.
patent: 4665210 (1987-05-01), Bitha et al.
patent: 4670458 (1987-06-01), Hlavka et al.
patent: 4673754 (1987-06-01), Smith et al.
patent: 4675336 (1987-06-01), Bitha et al.
patent: 4680308 (1987-07-01), Schwartz et al.
patent: 4707352 (1987-11-01), Stavrianpoulos
patent: 4720504 (1988-01-01), Andrulis, Jr. et al.
patent: 4739087 (1988-04-01), Speer et al.
International Search Report, PCT/U.S. 87/02996, 04/27/88.
Chem. Abstracts, vol. 107(25) #229147d (see therein JP87 59,289 (03/14/87).
Speer et al., "Antitumor Activity of Platinum Complexes of 1,2-Diaminocyclohexane Isomers", J. Clin. Hematology and Onocology, vol. 8, No. 2, 44-50(1978).
Dialog Search Report.
Lexis Search Report, Nov. 17, 1985.
Craciunescu et al., "On the Preparation, Antitumor and Cytotoxic Evaluation of Some New Analogs of the Cis-Dichloro (1,2-Diaminocyclohexane) Platinum(II) Complex", Eur. J. Med. Chem. Clin. Ther., vol. 19, 353-357 (1984).
Khokhar Abdul R.
Krakoff Irwin H.
Newman Robert A.
Shaver Paul F
The Board of Regents The University of Texas System
LandOfFree
1,2-diaminocyclohexane-platinum complexes with antitumor activit does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1,2-diaminocyclohexane-platinum complexes with antitumor activit, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2-diaminocyclohexane-platinum complexes with antitumor activit will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-641430