1,2-Carbamates of fortimicin B and derivatives

Details 1,2-Carbamates of fortimicin B and derivatives 1,2-Carbamates of fortimicin B and derivatives

1979-09-26

1981-05-26

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

548221, 424180, C07H 1522, C07D41302

Patent

active

042699703

ABSTRACT:
A 1,2-carbamate of fortimicin B and derivatives represented by the formula: ##STR1## wherein: R is hydrogen or monocyclicaryloxycarbonyl, R.sub.1 is hydrogen or monocyclicaryloxycarbonyl; and R.sub.2 is selected from the group consisting of loweralkyl, loweralkoxycarbonyl aminoloweralkyl, hydroxyloweralkyl, hydroxy-substituted aminolowerakyl, an amino acid residue, and N-protected amino acid residue, or when R and R.sub.1 are hydrogen, R.sub.2 can also be hydrogen; and the acid addition salts thereof when R,R.sub.1 or R.sub.2 are hydrogen or an unprotected aminoacid residue.

REFERENCES:
patent: 4065616 (1977-12-01), Umezawa et al.
patent: 4091032 (1978-05-01), Tadanier et al.
patent: 4169942 (1979-10-01), Mochda et al.
patent: 4176178 (1979-11-01), Martin et al.
Umezawa et al., Bulletin of Chemical Society of Japan, vol. 44, pp. 1411-1415, (1971).

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