1,2-bis (aminomethyl) cyclobutane-platinum complexes

Details 1,2-bis (aminomethyl) cyclobutane-platinum complexes 1,2-bis (aminomethyl) cyclobutane-platinum complexes

1990-09-25

1991-06-11

Straub, Gary P.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

556137, 548953, 548403, C07D 2500, C07F 1500

Patent

active

050233351

ABSTRACT:
1,2-Bis(aminomethyl)-cyclobutane-platinum complexes having an anti-tumor activity.

REFERENCES:
patent: 4322362 (1982-03-01), Kaplan et al.
patent: 4410544 (1983-10-01), Berg et al.
patent: 4482569 (1984-11-01), Butler et al.
Von Alessandro Pasini and Franco Zunion, "Neue Cisplatin-Analoga-" auf dem Weg zu besseren Cancerostatica, Angew Chem 99 (1987) pp. 632-641 (translation also attached).
Larry M. Hall, Robert J. Speer, Helen J. Ridgway, David P. Stewart, Andrew D. Newman and Joseph M. Hill, "Analogs of Sulfato 1,2-Diaminocyclohexane Platinium (II) (SHP) II, Modifications Other Than Leaving Ligand", Analogs of SHP: Non Leaving Ligands, vol. 7, No. 1, pp. 231-241.

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