1-[2-(.beta.Naphthyloxy)ethyl]-3-methylpyrazolone-(5) and antith

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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Details

424245, 260299, 260310A, 548367, A61K 31295, A61K 31415, C07D23108, C07F 1502

Patent

active

040536211

ABSTRACT:
1-[2-(.beta.-Naphthyloxy)ethyl]-3-methylpyrazolone-(5) and its salts are useful in the treatment and prophylaxis of thrombotic conditions. The compound is prepared through the reaction of 2-(.beta.-naphthyloxy)ethylhydrazine with either an acetoacetate or an ester of tetrolic acid, or through the condensation of 3-methylpyrazolinone-(5) with a derivative of 2-(.beta.-naphthyloxy)ethane, optionally with subsequent salt formation.

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