[1-(2-Benzoxazolyl)hydrazino]alkyl nitrile derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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548161, 548222, 548483, 424270, 424274, 424278, A61K 3142, C07D26358

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active

044761376

ABSTRACT:
Described are compounds of the formula ##STR1## wherein R is hydrogen or loweralkyl, X, Y and W independently of one another denote hydrogen, halogen, loweralkyl, nitro, amino, amido, loweralkoxy, hydroxy, nitrile, methylsulfone, methylsulfoxide, methylmercapto, or trifluoromethyl; Z is oxygen, sulfur or --CH.sub.2 ; n and m are each an integer from 0 to 6 inclusive, or pharmaceutically acceptable salts thereof.
The compounds are effective as anti-inflammatory agents.

REFERENCES:
patent: 3937714 (1976-02-01), Barnett
patent: 3981869 (1976-09-01), Ziemek
patent: 4178451 (1979-12-01), Wade et al.
patent: 4319026 (1982-03-01), Hedrich et al.
Nagarajan, K., et al., Indian Journal of Chemistry, vol. 9, pp. 748-754, (1971).

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