1,2-Benzisothiazolin-3-ones

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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Details

260304A, 544372, 546209, 424267, 424250, A61K 31425, C07D27762

Patent

active

041567293

ABSTRACT:
6-Substituted-1,2-benzisothiazolin-3-ones carrying an aminoalkyl group in the 2-position and being optionally substituted in the 4- and/or 5-position are antithrombotic agents. The compounds, of which 2-(2-diethylaminoethyl)-4,5-dimethyl-1,2-benzisothiazolin-3-one is a representative embodiment, can be prepared by cyclization of an appropriately substituted bis-[2-(aminoalkylcarbamyl)phenyl]disulfide, or by other disclosed methods.

REFERENCES:
patent: 3227715 (1966-01-01), Bub
patent: 4113728 (1978-09-01), Baggaley

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