1,2,5-thiadiazol-3,4-diamines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514183, 514212, 514362, 546209, 546246, 548135, 548569, 540480, 540603, 540450, 540609, 564501, 564511, A61K 31445, C07D40312

Patent

active

046633316

ABSTRACT:
This invention relates to Mannich-alkynyl aminothiadiazole oxides having histamine H.sub.2 -antagonist activity. A particular compound of this invention is 3-amino-4-[7-piperidinohept-5-ynylamino]-1,2,5-thiadiazole-1-oxide.

REFERENCES:
patent: 4374248 (1983-02-01), Crenshaw et al.
Resul, B., Dahlbom, R., Ringdahl, B., and Jenden, D., Eur. J. Med. Chem.--Chim. Ther., 1982-17, No. 4, pp. 317-322.

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