1,2,4-tribsubstituted benzenes as inhibitors of 15-lipoxygenase

Details 1,2,4-tribsubstituted benzenes as inhibitors of 15-lipoxygenase 1,2,4-tribsubstituted benzenes as inhibitors of 15-lipoxygenase

2005-06-14

2005-06-14

Shameem, Golam M M (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S490000

Reexamination Certificate

active

06906094

ABSTRACT:
The present invention provides compounds of formula (I) wherein R, Z, Y, W, R5, V, and X are as defined in the description, and pharmaceutically acceptable salts thereof, which are useful for the treatment of diseases responsive to the inhibition of the enzyme 15-lipoxygenase. Thus, the compounds of formula (I) and their pharmaceutically acceptable salts are useful for treating diseases with an inflammatory component, including atherosclerosis, diseases involving chemotaxis of monocytes, inflammation, stroke, coronary artery disease, asthma, arthritis, colorectal cancer, and psoriasis.

REFERENCES:
patent: 4595780 (1986-06-01), Ogata et al.
patent: 6268387 (2001-07-01), Connor et al.
patent: 2001/0031874 (2001-10-01), Connor et al.
patent: 4238233 (1994-05-01), None
patent: 0148725 (1985-07-01), None
patent: 9932433 (1999-07-01), None
patent: 0196299 (2001-12-01), None

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