[1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S252160, C514S259310, C544S114000, C544S262000

Reexamination Certificate

active

07598244

ABSTRACT:
Novel [1,2,4]triazolo[1,5-a]pyrimidine derivative of the general formula (1): (1) its prodrug or a pharmaceutically acceptable salt thereof, which exhibits an antigen presentation inhibiting activity and is useful as a preventive and/or therapeutic agent for immunological rejection and/or graft versus host reaction in organ/bone marrow transplant, autoimmune disease, allergic disease and/or inflammatory disease and also useful as an anticancer drug or as an immunological tolerance inducer for transplanted organ/transplanted bone marrow.

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Ralph, M. S. et al., Proceedings of the National Academy of Sciences of the United States of America, vol. 99, 351 (2002).
The European communication dated Oct. 23, 2007.

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