1,2,4-Triazoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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424250, 424251, 424258, 424263, 544235, 544238, 544295, 544296, 544333, 544357, 544405, 544331, 546276, 546283, 546284, A61K 3147, C07D40114

Patent

active

041985133

ABSTRACT:
Triazoles substituted at the 3 and 5 positions having an optional substituent in the 1 position are provided. Methods of preparing the novel substituted triazoles are described. The substituted triazoles are useful as anti-gout and anti-hyperuricemic agents. Compositions useful in the treatment of gout and hyperuricemia containing a substituted triazole as the active ingredient are also provided.

REFERENCES:
patent: 3308131 (1967-03-01), McKusick
Browne, et al., "J. Chem. Soc. (C)", 1968, pp. 824-830.
Browne, et al., "J. Chem. Soc. (C)", 1969, pp. 1056-1060.

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