Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1979-10-23
1983-10-11
Rollins, Alton D.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
424269, 542419, C07D24908
Patent
active
044093888
ABSTRACT:
Novel 1,2,4-triazole derivatives are described having the following formula ##STR1## wherein R represents hydrogen or methyl, R.sub.1 stands for hydrogen or (C.sub.1 -C.sub.4)alkyl, or R and R.sub.1 taken together may represent a further bond between the carbon atom and the oxygen atom, R.sub.2 and R.sub.4, each independently, represent hydrogen, chloro, fluoro, bromo, (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy, R.sub.3 stands for (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, allyloxy, propargyloxy, trifluoromethyl, phenyl, chloro, fluoro, bromo or dimethylamino or R.sub.3 and R.sub.4 taken together may represent a methylenedioxy group.
Also described is a process for their manufacture.
Use of the novel compounds as antireproductive agents and pharmaceutical compositions containing them as active ingredients are also claimed.
REFERENCES:
patent: 4119635 (1978-10-01), Omodei-Sale et al.
patent: 4151169 (1979-04-01), Omodei-Sale et al.
Pifferi et al., J. Heterocyclic Chemistry, vol. 9, pp. 581-586, (1972).
Consonni Pietro
Galliani Giulio
Omodei-Sale Amedeo
Gruppo Lepetit S.p.A.
Rollins Alton D.
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